Tacrolimus, (also FK-506 or Fujimycin), is a macrolide antibiotic available in a topical ointment that is used for the treatment of atopic dermatitis (eczema), a condition of itching, scaling, reddening, swelling, cracking, weeping, crusting, and inflammation of the skin as symptoms of an allergic reaction.  When applied directly on affected areas of the skin, tacrolimus suppresses the immune system reaction and the inflammation by inhibiting an enzyme (calcineurin) crucial T-cell multiplication.  It is sold under the trade name, Protopic.  To apply Protopic, apply a thin layer to the skin twice daily and follow the necessary precautions given by your doctor. 

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