Afrin (Oxymetazoline) is an over-the-counter topical decongestant which is used in products such as Nasivin, Vicks Sinex and Afrin. It is recommended for the temporary relief of nasal symptoms brought about by hay fever, respiratory allergies, colds, or sinusitis. It relieves stuffiness and congestion. The formulation is made to constrict the blood vessels in the nasal tissues that will lead to drainage and decongestion. Oxymetazoline is generally available as a nasal spray. The relief from each 2-3 sprays per nostril lasts 12 hours. It should be sprayed every 10-12 hours for no longer than 3-5 days.